American biotechnologists have, for the first time, restored youthful characteristics in aged human liver cells using epigenetic reprogramming. The company is preparing for clinical trials to confirm the effectiveness of this method and to expand its use for treating liver diseases and rejuvenating other tissues.
A study has shown that king penguins in zoos live longer than those in the wild, but their cells age faster due to constant feeding and low physical activity. While comfortable conditions increase their lifespan, they also shorten the period of biological youth.
For the first time, the technology of epigenetic cell rejuvenation, previously tested successfully on animals, is moving into clinical trials in humans. The new drug ER-100 could pave the way for restoring retinal cell function and treating age-related eye diseases.