A new test detects hazardous substances in products
Scientists have developed a fast and sensitive method for detecting unknown substances capable of damaging DNA in everyday products. This new approach allows for more effective identification of hazardous compounds even in complex mixtures, and can be used for routine quality control of products and water.
Cursus
A research team has developed a new, highly sensitive and rapid screening method that can detect previously unknown substances capable of altering DNA in common products such as skin creams, drinking water, and red meat.
The new testing procedure, presented at the University of Giessen, enables the identification of hidden chemical compounds that can irreversibly damage human DNA and harm living cells. Traditional methods often failed to detect such dangerous substances in complex mixtures due to solubility issues or interference with laboratory signals. To address this, the team created a method that isolates individual compounds from everyday items like tea, perfumes, and cosmetics, without needing prior knowledge of their chemical structure.
As part of the study, researchers simulated the function of the human liver to observe how the body processes these chemicals. They found that the natural detoxification of such compounds is extremely limited. Analysis of various mass-market products revealed harmful compounds in poorly regulated items, including lipsticks, wound ointments, and nipple creams.
The study results showed that hazardous substances can enter the bloodstream directly through microcracks in the skin or bleeding gums, bypassing the body's natural protective barriers. The findings also support existing warnings about the dangers of red meat and reinforce recent European Union bans on the use of smoke flavorings.
The updated screening procedure significantly increases the efficiency of laboratory research: compared to previous tests, the new method works five times faster, greatly reduces manual labor, and cuts consumable costs by more than 99%. To assist regulatory bodies and manufacturers in improving consumer safety, an accessible, open, and miniaturized version of the testing system has been created. This system can be implemented worldwide for regular quality control and environmental water monitoring.
